I had my T48S doing this. I have a locally hosted V16U5 install that is my local phone system, and a 16V5 hosted by a cloud provider that is our sister organizations system. I logged into the interface of my phone by web browser and configured account 2.
Whichever account receives a call will ring the phone and answering is accomplished the same at it always is, but to call from account 2 you need to use the 4-way button to switch to the second account (if I want to call an extension on account 2's 3cx instance, I have to select it by pressing the right arrow).
Its pretty simple as long as you get your info from the extension provisioning page and have the ports configured right.
oh, it cant be configured while you're in a call. That was a stupid half hour I wasted.