Sorry, not enough info for me to understand the issue.
I do not understand the "buttons at the top DIDs etc. are grayed out". A screen shot or some added details might be helpful.
Normally, when something is grayed out, it is due to that function not being available, This is normally due to the version of 3CX not supporting say, certain call strategies as you do not have the Pro/CCE edition or a license issue in that it is not activated which then opens the functionality.