No, just uploaded a newer ISO as my Debians were all 8.x so needed an update.
Network etc all the same. Also acts as a good DR with the newer ISO as you can just spin up a new 3CX so quickly on VMs.
Have done similar with Windows 10 installs that I have moved to the cloud - simply removed the 3CX prog from the Win 10 PC, then used it as an SBC on site instead, with a Raspberry as backup. Same sort of scenario, as also a DR option there.